WebApr 11, 2015 · We undertook a meta-analysis of statin trials in the Cholesterol Treatment Trialists' (CTT) Collaboration database to compare the effects of statin therapy between women and men. Interpretation: In men and women at an equivalent risk of cardiovascular disease, statin therapy is of similar effectiveness for the prevention of major vascular … WebApr 13, 2024 · Specifically, we calibrated the rate ratio (RR) for ASCVD events associated with a 39 mg/dL reduction in LDL-C from a meta-analysis by the Cholesterol Treatment …
Protocol for a prospective collaborative overview of all ... - PubMed
WebFeb 4, 2024 · In the 28 trials of 186,854 participants, 8% (14,483) were >75 years at baseline and median follow-up was 4.9 years. There was a 21% proportional reduction in major CVEs per 1.0 mmol/L reduction in LDL-C, which decreased insignificantly with age and significantly in all age groups. Overall, statin or more intensive statin therapy yielded … WebBaigent C, Blackwell L, Emberson J, et al; Cholesterol Treatment Trialists’ (CTT) Collaboration. Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials. Lancet. 2010;376(9753):1670-1681.PubMed Google Scholar Crossref running iowa
National Center for Biotechnology Information
WebThe secretariat of the Cholesterol Treatment Trialists' Collaboration was established to coordinate the prospective meta-analysis. Individual patient data (IPD) were checked for internal consistency and completeness of … Weba concern in the medical community. In the Cholesterol Trialist Collaboration, lowering LDL cholesterol by 2 mmol/L (78 mg/dL) in 10000 patients with previous symptomatic vascular disease would prevent 1000 major vascular events and cause 5 to 10 ICH.3 Trials in sec-ondary prevention of stroke showed a 1.7-fold relative WebJun 1, 1995 · Cholesterol Treatment Trialists' (CTT) Collaboration The Cholesterol Treatment Trialists' Collaboration aims to provide reliable information about the effects on mortality and morbidity of treatments that modify blood lipid levels for a wide range of patient populations and risk groups. sccc parking permit