The primary use of clofazimine is for the treatment of leprosy.Other uses have not been proven to be safe or effective. It has been studied in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in people with HIV/AIDS and Mycobacterium avium paratuberculosis. … See more Clofazimine produces pink to brownish skin pigmentation in 75-100% of patients within a few weeks, as well as similar discoloration of most bodily fluids and secretions. These … See more Clofazimine has a biological half life of about 70 days. Autopsies performed on those who have died while on clofazimine show crystal-like aggregates in the intestinal mucosa, … See more Clofazimine works by binding to the guanine bases of bacterial DNA, thereby blocking the template function of the DNA and inhibiting bacterial proliferation. It also increases activity of … See more Clofazimine, initially known as B663, was first synthesised in 1954 by a team of scientists at Trinity College, Dublin: Frank Winder, J.G. Belton, Stanley McElhinney, M.L. Conalty, Seán O'Sullivan, and Dermot Twomey, led … See more Webskin or soft tissue infections. Also reported were 2 corneal, 1 peritoneal, 1 catheter-related, and 1 pacemaker pocket ... clofazimine, 1 *IV, intravenous. †Therapy was started for 34 patients, but 1 initial regimen was unknown. Treatment of Mycobacterium abscessus Infection Side effects were common; 74 side effects were docu-mented among 34 ...
Clofazimine: Generic, Uses, Side Effects, Dosages ... - RxList
WebYes, Clofazimine may cause orange-pink to brownish-black discoloration of the skin within a few weeks after you start using it. This skin discoloration may take several months or years to resolve even after completion of your treatment with Clofazimine. Such conditions may cause the patient to become depressed or the patient may develop ... WebApr 13, 2024 · For clofazimine, it is noted that discoloration of the skin may occur (LactMed ®). Because of a possible influence on the gastrointestinal flora, infants whose nursing mothers receive levofloxacin should be monitored … seller finance homes near me
Side Effects of Lamprene (Clofazimine), Warnings, Uses - RxList
WebApr 30, 2024 · Skin pigmentation from clofazimine therapy in leprosy patients: a reappraisal. J Am Acad Dermatol. 1990 Aug. 23(2 Pt 1):236-41. [QxMD MEDLINE Link]. MacMorran WS, Krahn LE. Adverse cutaneous reactions to psychotropic drugs. Psychosomatics. 1997 Sep-Oct. 38(5):413-22. [QxMD MEDLINE Link]. Wolf ME, Richer … Webon leprosy patients, clofazimine crystals were found predominantly in the mesenteric lymph nodes, adrenals, subcutaneous fat, liver, bile, gall bladder, spleen, small intestine, … WebWhat are the side effects of clofazimine? Skin discolouration: reddish to brownish-black colour, particularly in fair-skinned patients at sites exposed to light. Scaly and dry skin … seller finance a bank owned home