Tsc1f/f

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August undefined, 2024

WebTSC1-conditional knockout (DMP1-Cre+ ; TSC1f/f , hereafter CKO) mice and littermate control (DMP1-Cre- ; TSC1f/f , hereafter WT) mice were generated. H&E staining, … WebJan 29, 2024 · Europe PMC is an archive of life sciences journal literature.

Hepatocytic p62 suppresses ductular reaction and tumorigenesis …

WebOverall design: p62F/F and Tsc1 F/F mice (Mori et al., 2009; Muller et al., 2013) were backcrossed to C57BL/6 mice for at least 7 generations, and then bred with Alb-Cre transgenic mice (also on C57BL/6 background) to generate p62F/F; Alb-Cre (p62Δhep) and Tsc1F/F; Alb-Cre (Tsc1Δhep)mice, respectively. p62Δhep mice were crossed to Tsc1Δhep ... WebDec 12, 2014 · genotype: Tsc1f/f, Mx1-Cre+ (Cre positive cKO): KO LSK 1, KO LSK 2, KO LSK 3, KO LSK 4 biological replicate: WT LSK 1, WT LSK 2, WT LSK 3, WT LSK 4 biological replicate: KO LSK 1, KO LSK 2, KO LSK 3, KO LSK 4 : Contributor(s) Ye P, Liu Y, Chen C, Tang F, Wu Q, Wang X, Liu C, Liu X, Liu R, Liu Y, Zheng P: Citation missing: Has this study been ... greatest prime factor of 32

Tsc1 ablation in Prx1 and Osterix lineages causes renal …

WebJun 10, 2024 · MATERIALS AND METHODS Mice. TSC1f/f mice and OT1 mice were from The Jackson Laboratory, while CD4Cre mice were from Taconic Farms. Mice were housed … WebE, the brain tissues from WT mice, Tsc1f/f Syn1Cre mice, and Tsc1f/f Syn1Cre mice treated with rapamycin (R) (Tsc1f/f Syn1Cre +R) were immunoblotted. F, HepG2, Bel-7402, SK-HEP-1, A549, and ELT3 cells were treated with or without 10 n m rapamycin (R) for 24 h and then subjected to immunoblotting. WebCatalogue Number 160865: Antigen/Gene or Protein Targets Tsc1/Hamartin greatest prime factor of 100

For competitive adoptive transfers, equal numbers of naive WT …

GEO Accession viewer - National Center for Biotechnology …

WebJan 12, 2024 · CD11c Cre, Tsc1 f/f, Raptor f/f, OT-I and OT-II mice were purchased from Jackson Laboratories (Bar Harbor, ME, USA). All used mice have been backcrossed with … WebFeb 1, 2024 · TSC1-conditional knockout (DMP1-Cre+ ; TSC1f/f , hereafter CKO) mice and littermate control (DMP1-Cre- ; TSC1f/f , hereafter WT) mice were generated. H&E … flip phones no internetWebThe TSC1 gene provides instructions for producing a protein called hamartin. Within cells, hamartin interacts with a protein called tuberin, which is produced from the TSC2 gene. These two proteins help control cell growth and division (proliferation) and cell size. Proteins that normally prevent cells from growing and dividing too fast or in ... flip phones sass

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Tsc1f/f

Abstract 1831: Role of autophagy in lymphangiosarcoma initiation …

WebJul 7, 2024 · GEO help: Mouse over screen elements for information. p62/SQSTM1 is a ubiquitin-binding autophagy receptor and signaling protein that accumulates in … Web153. Maira S, Stauffer F, Brueggen J, Furet P, Schnell C, Fritsch C, et al. Identification and char-acterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/ mammalian target of rapamycin inhibitor with potent in vivo antitumor activity. Mol Cancer Ther 2008; 7:1851-63. 154.

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WebThe bronchiole is a major site for the development of several life‐threatening disorders including chronic obstructive pulmonary disease and lung adenocarcinomas. The bronchiolar epithelium is ... WebApr 14, 2024 · LOS ANGELES, April 14, 2024 /PRNewswire/ -- Aadi Bioscience, Inc. (NASDAQ: AADI), a commercial-stage biopharmaceutical company focused on developi...

Webgenotype/variation: TSC1f/f / p62f/f mice AlbCre positive - Specific deletion of TSC1 and p62 in hepatocytes Growth protocol p62F/F and Tsc1 F/F mice (Mori et al., 2009; Muller et al., … WebBoth TSC1f/f LysM-Cre+ and LysM-Cre- mice were aerogenously infected with M. tuberculosis H37Rv with 200-300 bacilli per lung. Bacterial burdens were measured by …

WebWe allowed Tsc1f/f; Rosa26-CreERT2 glioma cells to form spheres in culture and then added 4-hydroxytamoxifen (4-OHT) to delete the Tsc1 gene. First, we confirmed that 4-OHT efficiently induced Tsc1 deletion in these sphere cells, as evidenced by the disappearance of TSC1 protein from lysates of sphere cells that had been cultured with 4-OHT ( Fig. 2 A ). WebOn the other hand, Tsc1 deficiency in the Dermo1 lineage did not produce detectable phenotypical changes in the kidney. Cyst formation in Prx1-Cre; Tsc1f/f and Osx-Cre; …

WebMay 30, 2013 · Caroline F. Bruinsma MSc. Department of Neuroscience, Erasmus University Medical Center, Rotterdam, the Netherlands. ENCORE Expertise Center for …

WebNCBI's Gene Expression Omnibus (GEO) is a public archive and resource for gene expression data. flip phones security vs smartphonesWebDownload scientific diagram Metabolic assessment of rip-Cre tsc1 f/f and rip-Cre tsc1f/f, tsc2 f/f. random glucose (a) and insulin (B) levels obtained in the same group and age of … greatest prewar footballersWebmTORC1 is a key regulator of cell metabolism and lymphocyte proliferation. mTORC1 is inhibited by the tuberous sclerosis complex (TSC), a heterodimer of TSC1 and TSC2. Deletion of either genes results in robust activation of mTORC1. Mature B cells greatest presidents in american historyWebEntdecke Style Council 7" Vinyl Single Schallplatte Speak Like A Child UK TSC1 POLYDOR 1983 in großer Auswahl Vergleichen Angebote und Preise Online kaufen bei eBay Kostenlose Lieferung für viele Artikel! greatest prime factor of 48WebJul 1, 2024 · FIP200 (FAK family interacting protein of 200 kDa) was identified as an essential autophagy gene, which was shown to play a key role in breast cancer development and progression. By crossing Tsc1f/f, Scl-Cre mice with Fip200f/f mice, we generated Tsc1/Fip200 double cKO mice. greatest president of the philippinesWebDec 16, 2009 · Introduction. The phosphatidylinositol 3-kinase (PI3K) pathway (Fig. 1) plays a pivotal role in cell growth, proliferation and survival [] and signalling via this pathway is upregulated in many types of cancer [2, 3].Genomic alterations have been detected in multiple genes in the pathway. These include the tumour suppressor genes PTEN and … greatest presidents of usaWebDownload scientific diagram Treatment with the TORC1 inhibitor rapamycin (rapa; 10 mg/kg) after seizure onset abolishes seizures in Tsc1f/− mice. (A) Timeline (days) of … greatest potential stocks